The serum concentration of Atorvastatin can be decreased when it is combined with Dabrafenib. Standardized susceptibility test procedures require the use of laboratory control microorganisms to control the technical aspects of the laboratory procedures. The serum concentration of Calcidiol can be decreased when it is combined with Orlistat. The metabolism of Ropinirole can be decreased when combined with Itraconazole. In most cases therapy with chloramphenicol had been instituted within the first 48 hours of life. Spironolactone is frequently used as a component of feminizing hormone therapy in transgender women, especially in the United States (where cyproterone acetate is not available), usually in addition to an estrogen.

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