About 3% to 4% is excreted in the urine as unchanged drug. Use Tretinoin Cream, USP (Emollient) as part of a total skin care and sunlight avoidance program. The therapeutic efficacy of Rosiglitazone can be decreased when used in combination with Estrone sulfate. They should completely avoid this drug. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns. Neonates whose mothers received propranolol at parturition have exhibited bradycardia, hypoglycemia, and/or respiratory depression.

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